New York City Economic Development Corporation (NYCEDC) developed the Global Business Exchange to partner with major cities around the world in a shared commitment to global entrepreneurship and innovation. The exchange connects local companies to international opportunities, helping them overcome barriers that inhibit entry into foreign markets.

In October, 2015, the first Global Business Exchange was launched in partnership with the City of Paris. The companies participating in the exchange started their time in each city in March 2016, and will be there until August. Applications for the next Global Business Exchange, in partnership with the City of Milan, will open on May 16th, 2016. Programming will begin in September 2016 and run until March 2017.